A Minute Small-Cell Lung Cancer Showing a Latent Phase Early in Growth

Haruhiko Nakamura, MD,PhD,1 Norihito Kawasaki, MD,1 Masahiko Taguchi, MD,PhD,1 and Hajime Kitamura, MD,PhD2

A minute small-cell lung cancer measuring 8×5 mm was detected and serially imaged by computed tomography for about a year preceding resection. Although this solid nodule showed a short overall doubling time (76 days), the growth curve included an early phase without apparent growth prior to the phase of rapid growth. Accordingly, lung cancer cannot be ruled out when a small nodule (<10 mm) does not enlarge in the first several months of computed tomographic follow-up. (Ann Thorac Cardiovasc Surg 2007; 13: 254-257)

Key words: computed tomography, growth curve, imaging, lobectomy, small-cell lung cancer

Departments of 1Chest Surgery and 2Pathology, Atami Hospital, International University of Health and Welfare, Atami, Japan

Received October 31, 2006; accepted for publication November 22, 2006
Address reprint requests to Haruhiko Nakamura, MD, PhD: Department of Chest Surgery, Atami Hospital, International University of Health and Welfare, 13–1 Higashikaigan-cho, Atami, Shizuoka 413–0012, Japan.